Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31136536 | 0.79 | QDPR (0.33) | PRCP | |
| SCHEMBL9477025 | 0.78 | PRCP (0.59) | PRCP | |
| SCHEMBL9639284 | 0.78 | PRCP (0.59) | PRCP | |
| SCHEMBL9477017 | 0.78 | PRCP (0.59) | PRCP | |
| SCHEMBL31137710 | 0.76 | PNMT (0.39) | CYP1A2CYP2D6CYP2C19KMT2ALMNA | |
| SCHEMBL31136367 | 0.76 | KMT2A (0.49) | CYP2D6KMT2A | |
| SCHEMBL29960816 | 0.75 | HTR2A (0.37) | CYP2D6 | |
| SCHEMBL31137587 | 0.74 | PRCP (0.50) | PRCP | |
| SCHEMBL31513971 | 0.74 | PRCP (0.50) | PRCP | |
| Hydrochloric Acid SCHEMBL29960697 | 0.74 | TAAR1 (0.37) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108997-A | Diuretic [2]benzopyrano[4,3-b]pyridines and process therefor | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-08-22 | — | — | US | disclosed |
| US-4108997-A | Diuretic [2]benzopyrano[4,3-b]pyridines and process therefor | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-08-22 | — | — | US | disclosed |