Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.56 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397821 | 0.89 | CTSK (0.55) | CTSKCTSBCTSLCTSHPSMB1 | |
| SCHEMBL20953619 | 0.88 | CTSK (0.55) | CTSKCTSBCTSLCTSHPSMB1 | |
| SCHEMBL14285574 | 0.88 | CTSK (0.55) | CTSKCTSBCTSLCTSHPSMB1 | |
| SCHEMBL8527341 | 0.87 | CTSK (0.53) | CTSKCTSBCTSLCTSHPSMB1 | |
| SCHEMBL11888311 | 0.87 | CTSK (0.53) | CTSKCTSBCTSLCTSHPSMB1 | |
| SCHEMBL14527881 | 0.86 | CTSK (0.65) | CTSKCTSBCTSLCTSH | |
| SCHEMBL7417702 | 0.86 | CTSK (0.65) | CTSKCTSBCTSLCTSH | |
| SCHEMBL115059 | 0.85 | CTSL (0.52) | CTSBCTSL | |
| SCHEMBL7732224 | 0.85 | CTSK (0.63) | CTSKCTSBCTSLCTRB1 | |
| SCHEMBL5275932 | 0.85 | CTSK (0.59) | CTSKCTSBCTSLCTSHPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | CTSK 1607/4885CTSB 475/4885CTSL 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.