Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211717 | 0.78 | KMT2A (0.63) | PKMTDP1DHFRTSHRSMN1; SMN2 | |
| SCHEMBL11665634 | 0.78 | ALDH3A1 (0.43) | TDP1KMT2AMEN1CA2CA12 | |
| SCHEMBL8548451 | 0.78 | CA2 (0.68) | SMN1; SMN2KMT2AMEN1CA2CA12 | |
| SCHEMBL5700398 | 0.76 | PTGS2 (0.42) | PKMTDP1KMT2AMEN1MAPT | |
| SCHEMBL11638120 | 0.76 | GAA (0.42) | TDP1KMT2ACA2CA12CA9 | |
| SCHEMBL11642938 | 0.75 | MEN1 (0.51) | KMT2AMEN1CA2CA12CA9 | |
| SCHEMBL11667035 | 0.74 | ALDH1A1 (0.46) | TDP1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11665577 | 0.73 | MAPT (0.48) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL11667095 | 0.73 | MEN1 (0.49) | PKMSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL1491205 | 0.73 | KMT2A (0.42) | KMT2AMEN1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094982-A | PYRIDINE SULFONAMIDES AND THEIR USE AS ANTICOCCIDIAL AGENTS | SANKYO COMPANY LIMITED (JA) | 1978-06-13 | — | — | US | claimed |
| US-4094982-A | PYRIDINE SULFONAMIDES AND THEIR USE AS ANTICOCCIDIAL AGENTS | SANKYO COMPANY LIMITED (JA) | 1978-06-13 | — | — | US | disclosed |