Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31692111 | 0.95 | TDP1 (0.54) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL19668428 | 0.95 | TDP1 (0.54) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7116077 | 0.82 | CYP1A2 (0.52) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6221568 | 0.81 | PTGDR2 (0.57) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7804236 | 0.80 | GRM4 (0.64) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11555227 | 0.79 | L3MBTL1 (0.57) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10675993 | 0.79 | LMNA (0.57) | TDP1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL11358956 | 0.79 | L3MBTL1 (0.57) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL22414714 | 0.78 | ROCK2 (0.53) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL26363863 | 0.78 | L3MBTL1 (0.49) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111962-A | Certain substituted 2-phenylnaphtho[1,2-b]furane and -[2,1-b]furane | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |