Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11643261 | 0.78 | TDP1 (0.53) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL22414714 | 0.75 | ROCK2 (0.53) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9787048 | 0.74 | L3MBTL1 (0.73) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL31692111 | 0.73 | TDP1 (0.54) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL19668428 | 0.73 | TDP1 (0.54) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1312768 | 0.72 | PTPN7 (0.72) | TDP1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL9925462 | 0.72 | KDM4E (0.68) | L3MBTL1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL6224144 | 0.71 | ALDH1A1 (0.73) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1068092 | 0.70 | MAPT (0.69) | L3MBTL1TDP1KMT2AMEN1KDM4E | |
| SCHEMBL9786970 | 0.70 | MAPT (0.74) | L3MBTL1TDP1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249556-A2 | POLYPROPYLENE COPOLYMER COMPOSITION HAVING SUBZERO IMPACT RESISTANCE | W.R. Grace & CO. - CONN. (US) | 2023-09-27 | — | — | EP | disclosed |