Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 8/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MDH1 | P40925 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.47 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.47 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11643740 | 0.92 | MTNR1B (0.54) | MTNR1BMTNR1APOLBMDH1ALDH1A1 | |
| SCHEMBL11642100 | 0.88 | MDH1 (0.58) | MTNR1BMTNR1APOLBMDH1ALDH1A1 | |
| SCHEMBL11640331 | 0.87 | POLB (0.65) | MTNR1BMTNR1ALTA4HPOLBMDH1 | |
| SCHEMBL11643300 | 0.84 | LTA4H (0.54) | MTNR1BMTNR1ALTA4H | |
| SCHEMBL11644190 | 0.80 | MTNR1B (0.78) | MTNR1BMTNR1AHPGD | |
| SCHEMBL11641172 | 0.80 | LTA4H (0.67) | MTNR1BMTNR1ALTA4HPOLBALDH1A1 | |
| SCHEMBL11645169 | 0.80 | MTNR1A (0.53) | MTNR1BMTNR1ALTA4HPOLBMDH1 | |
| SCHEMBL688080 | 0.78 | PLK1 (0.53) | MTNR1BMTNR1A | |
| SCHEMBL11644529 | 0.78 | POLB (0.49) | LTA4HPOLBMDH1ALDH1A1HPGD | |
| SCHEMBL11644373 | 0.78 | MTNR1B (0.53) | MTNR1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |