Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | IL18 | Q14116 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644971 | 0.88 | LTA4H (0.47) | LTA4HS1PR1S1PR3HDAC8LMNA | |
| SCHEMBL11639881 | 0.88 | LTA4H (0.59) | LTA4HS1PR1S1PR3HDAC8KMT2A | |
| SCHEMBL11645656 | 0.85 | LMNA (0.60) | LTA4HS1PR1S1PR3HDAC8KMT2A | |
| SCHEMBL11691654 | 0.85 | ALDH1A1 (0.61) | LTA4HS1PR1S1PR3HDAC8KMT2A | |
| SCHEMBL11643760 | 0.85 | S1PR1 (0.57) | LTA4HS1PR1S1PR3HDAC8KMT2A | |
| SCHEMBL11643286 | 0.85 | LTA4H (0.56) | LTA4HKCNA5S1PR1S1PR3HDAC8 | |
| SCHEMBL11644742 | 0.84 | S1PR1 (0.59) | LTA4HS1PR1S1PR3HDAC8KMT2A | |
| SCHEMBL11644156 | 0.82 | SMN1; SMN2 (0.56) | LTA4HS1PR1S1PR3HDAC8MAPT | |
| SCHEMBL11647275 | 0.82 | S1PR1 (0.58) | LTA4HS1PR1S1PR3HDAC8LMNA | |
| SCHEMBL11647845 | 0.82 | S1PR1 (0.58) | LTA4HS1PR1S1PR3HDAC8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |