Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PFKFB2 | O60825 | 5/20 | 0.52 |
| ▸ | PFKFB3 | Q16875 | 5/20 | 0.52 |
| ▸ | PFKFB1 | P16118 | 4/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | AS3MT | Q9HBK9 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645520 | 0.87 | ALDH1A1 (0.56) | HPGDPOLBMAPTALDH1A1KMT2A | |
| SCHEMBL11646606 | 0.84 | LTA4H (0.62) | HPGDPOLBMAPTALDH1A1KMT2A | |
| SCHEMBL11645836 | 0.84 | ALDH1A1 (0.52) | HPGDPFKFB2PFKFB3PFKFB1NSD2 | |
| SCHEMBL11641172 | 0.83 | LTA4H (0.67) | POLBALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL11642665 | 0.81 | L3MBTL1 (0.63) | HPGDMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11645672 | 0.81 | MEN1 (0.60) | POLBMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL13832459 | 0.81 | MTNR1B (0.52) | HPGDMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11648480 | 0.80 | SMN1; SMN2 (0.66) | HPGDPOLBPFKFB2PFKFB3PFKFB1 | |
| SCHEMBL11644190 | 0.80 | MTNR1B (0.78) | HPGDMTNR1AMTNR1B | |
| SCHEMBL11645364 | 0.80 | RNF4 (0.71) | HPGDPOLBMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |