Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | HBB | P68871 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27305127 | 0.83 | HSP90AB1 (0.52) | MEN1KMT2ATDP1MAPK1CYP3A4 | |
| SCHEMBL9846966 | 0.77 | ALDH1A1 (0.55) | MEN1KMT2ATDP1MAPK1CYP3A4 | |
| SCHEMBL9846962 | 0.77 | ALDH1A1 (0.55) | MEN1KMT2ATDP1MAPK1CYP3A4 | |
| Phenazopyridine SCHEMBL253232 | 0.74 | MEN1 (1.00) | MEN1KMT2ATDP1MAPK1CYP3A4 | |
| Phenazopyridine SCHEMBL360809 | 0.74 | MEN1 (1.00) | MEN1KMT2ATDP1MAPK1CYP3A4 | |
| Phenazopyridine SCHEMBL14340038 | 0.74 | MEN1 (1.00) | MEN1KMT2ATDP1MAPK1CYP3A4 | |
| SCHEMBL10708407 | 0.73 | MAPT (0.64) | MEN1KMT2ATDP1MAPK1CYP3A4 | |
| SCHEMBL10708396 | 0.73 | MAPT (0.64) | MEN1KMT2ATDP1MAPK1CYP3A4 | |
| Phenazopyridine SCHEMBL26499 | 0.73 | MAPT (1.00) | MEN1KMT2ATDP1MAPK1CYP3A4 | |
| Phenazopyridine SCHEMBL14687482 | 0.73 | MAPT (1.00) | MEN1KMT2ATDP1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083841-A | FOLIC ACID ANTAGONISTS | SHAW UNIVERSITY (US) | 1978-04-11 | — | — | US | disclosed |