Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817147 | 0.79 | CYP1A2 (0.59) | SMN1; SMN2PDE4BALDH1A1MAPTOPRM1 | |
| SCHEMBL11654832 | 0.77 | CYP1A2 (0.61) | SMN1; SMN2ALDH1A1MAPTTP53NPC1 | |
| SCHEMBL29397663 | 0.75 | MAPK14 (0.43) | FLT3SMN1; SMN2MAPK11MAPK14PDE4B | |
| SCHEMBL1011502 | 0.75 | MAPK14 (0.43) | FLT3SMN1; SMN2MAPK11MAPK14PDE4B | |
| SCHEMBL11656306 | 0.74 | LMNA (0.51) | SMN1; SMN2ALDH1A1MAPTTP53NPC1 | |
| SCHEMBL6676733 | 0.72 | RXRA (0.50) | TMEM97SIGMAR1 | |
| SCHEMBL2318517 | 0.72 | KDM4E (0.40) | FLT3SMN1; SMN2MAPK11MAPK14PDE4B | |
| SCHEMBL12361530 | 0.72 | RXRA (0.43) | FLT3MAPK11MAPK14KCNN4SLC16A3 | |
| SCHEMBL27836980 | 0.71 | CNR2 (0.46) | SMN1; SMN2MAPK14PDE4BALDH1A1OPRM1 | |
| SCHEMBL14357204 | 0.70 | PDE4B (0.62) | SMN1; SMN2PDE4BALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097475-A | FOR POLYESTERS AND BLENDS WITH CELLULOSE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-27 | — | — | US | disclosed |