Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367665 | 1.00 | CYP19A1 (0.61) | CYP19A1TSHRKIF11MAPK1HIF1A | |
| SCHEMBL1224870 | 1.00 | CYP19A1 (0.61) | CYP19A1TSHRKIF11MAPK1HIF1A | |
| SCHEMBL7782036 | 0.89 | CYP19A1 (0.65) | CYP19A1TSHRMAPK1HIF1AMEN1 | |
| Chlorotriphenylmethane SCHEMBL461 | 0.86 | TSHR (0.65) | CYP19A1TSHRMAPK1CYP1A2 | |
| Chlorotriphenylmethane SCHEMBL16781670 | 0.86 | TSHR (0.65) | CYP19A1TSHRMAPK1CYP1A2 | |
| SCHEMBL3903209 | 0.84 | TSHR (0.50) | CYP19A1TSHRKIF11MAPK1HIF1A | |
| SCHEMBL7646185 | 0.84 | TSHR (0.50) | CYP19A1TSHRKIF11MAPK1HIF1A | |
| SCHEMBL9577502 | 0.84 | TSHR (0.74) | CYP19A1TSHRKIF11MAPK1HIF1A | |
| Chlorotriphenylmethane SCHEMBL7567317 | 0.83 | TSHR (0.61) | CYP19A1TSHRMAPK1CYP1A2 | |
| Chlorotriphenylmethane SCHEMBL7246540 | 0.83 | TSHR (0.61) | CYP19A1TSHRMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647745-B2 | Compound for treating sequelae of ischemic cerebral stroke | Wang, Jingyi (CN) | 2020-05-12 | — | — | US | disclosed |
| EP-3130600-B1 | A COMPOUND FOR TREATING SEQUELAE OF ISCHEMIC CEREBRAL STROKE | WANG JINGYI (CN) | 2019-03-27 | — | — | EP | disclosed |
| US-20190040101-A1 | COMPOUND FOR TREATING SEQUELAE OF ISCHEMIC CEREBRAL STROKE | WANG, JINGYI (CN) | 2019-02-07 | — | — | US | disclosed |
| US-20170044212-A1 | COMPOUND FOR TREATING SEQUELAE OF ISCHEMIC CEREBRAL STROKE | WANG JINGYI (CN) | 2017-02-16 | — | — | US | disclosed |
| EP-3130600-A1 | A COMPOUND FOR TREATING SEQUELAE OF ISCHEMIC CEREBRAL STROKE | Wang, Jingyi (CN) | 2017-02-15 | — | — | EP | disclosed |
| US-4098894-A | FUNGICIDES AND BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044212-A1 | COMPOUND FOR TREATING SEQUELAE OF ISCHEMIC CEREBRAL STROKE | CHRNA7, CHRNA4, CHRNA3 | CYP19A1 3744/4885TSHR 1040/4885KIF11 2283/4885 |
| US-10647745-B2 | Compound for treating sequelae of ischemic cerebral stroke | CHRNA7, CHRNA4, CHRNA3 | CYP19A1 3744/4885TSHR 1040/4885KIF11 2283/4885 |
| US-20190040101-A1 | COMPOUND FOR TREATING SEQUELAE OF ISCHEMIC CEREBRAL STROKE | CHRNA7, CHRNA4, CHRNA3 | CYP19A1 3744/4885TSHR 1040/4885KIF11 2283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.