SCHEMBL11652182

SCHEMBL11652182

CC(C)N1C(=O)CC(=O)N(c2ccccc2)C1=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.46
GAA P10253 5/20 0.44
PKM P14618 1/20 0.44
TLR9 Q9NR96 1/20 0.44
OPRK1 P41145 1/20 0.42
PDE4D Q08499 1/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPT P10636 3/20 0.42
ALDH1A1 P00352 6/20 0.42
NPSR1 Q6W5P4 1/20 0.40
KDM4E B2RXH2 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MGLL Q99685 1/20 0.38
ENPP2 Q13822 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11656161 0.85 MAPT (0.50) HPGDGAATLR9MEN1KMT2A
SCHEMBL7044709 0.83 HPGD (0.56) HPGDGAAPKMTLR9OPRK1
SCHEMBL9184671 0.83 HPGD (0.41) HPGDGAAPKMTLR9OPRK1
SCHEMBL17717909 0.82 HPGD (0.40) HPGDGAAPKMTLR9OPRK1
SCHEMBL437784 0.81 HPGD (0.59) HPGDGAAPKMTLR9OPRK1
SCHEMBL11745637 0.78 KMT2A (0.49) HPGDMEN1KMT2AMAPTL3MBTL1
SCHEMBL12081988 0.77 MEN1 (0.64) HPGDGAAPKMTLR9OPRK1
SCHEMBL22580612 0.77 MEN1 (0.64) HPGDGAAPKMTLR9OPRK1
SCHEMBL5437358 0.77 OPRK1 (0.56) HPGDGAAPKMTLR9OPRK1
SCHEMBL13241600 0.76 CTSG (0.45) HPGDGAATLR9MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4097475-A FOR POLYESTERS AND BLENDS WITH CELLULOSE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-27 US disclosed