Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11653443 | 0.88 | MAPT (0.35) | KMT2AMEN1NPSR1MAPTHPGD | |
| SCHEMBL11653345 | 0.76 | EGLN2 (0.40) | KMT2AMEN1NPSR1HPGDPKM | |
| SCHEMBL11651190 | 0.76 | EGLN2 (0.40) | PKMPTGS2PTGS1RAB9AEGLN2 | |
| SCHEMBL11652662 | 0.76 | PARP15 (0.54) | KMT2AMEN1NPSR1MAPTHPGD | |
| SCHEMBL11651408 | 0.75 | TDP1 (0.37) | MAPTPKMPTGS2MAPK1HTT | |
| SCHEMBL11647514 | 0.71 | PTGS1 (0.41) | KMT2APTGS2PTGS1ALDH1A1TDP1 | |
| SCHEMBL11652353 | 0.68 | ALDH1A1 (0.53) | KMT2AMEN1NPSR1HPGDPKM | |
| SCHEMBL11653522 | 0.64 | TP53 (0.39) | KMT2AMEN1MAPTPTGS2ALDH1A1 | |
| SCHEMBL29985931 | 0.61 | GABRA1 (0.46) | KMT2AMEN1ALDH1A1RAB9AHTT | |
| SCHEMBL1766101 | 0.61 | GABRA1 (0.46) | KMT2AMEN1ALDH1A1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075218-A | INSECTICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3974286-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1976-08-10 | — | — | US | disclosed |