Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL11658000 | 0.81 | ALDH1A1 (0.48) | DHODHLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL26986682 | 0.77 | ALDH1A1 (0.46) | LMNATSHRKDM4EALOX15ACMSD | |
| SCHEMBL30712643 | 0.77 | ALDH1A1 (0.46) | LMNATSHRKDM4EALOX15ACMSD | |
| SCHEMBL2837730 | 0.77 | KDM4E (0.54) | DHODHPDE10ALMNATSHRKDM4E | |
| SCHEMBL2114841 | 0.74 | GRM2 (0.61) | PDE10ALMNAKDM4EALOX15ALDH1A1 | |
| SCHEMBL6052793 | 0.74 | MMP2 (0.53) | KDM4ETDP1ALDH1A1RAB9AMCL1 | |
| SCHEMBL10985563 | 0.74 | KDM4E (0.48) | DHODHPDE10ALMNATSHRKDM4E | |
| SCHEMBL13321751 | 0.73 | MMP2 (0.53) | DHODHLMNACYP3A4CYP2C8CYP2C9 | |
| SCHEMBL15439882 | 0.72 | PIK3CA (0.48) | DHODHTSHRKDM4EALOX15ACMSD | |
| SCHEMBL1759786 | 0.71 | MCL1 (0.64) | TSHRKDM4EALOX15ACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093622-A | Pyridine esters of cyclopropane-carboxylic acid | ZOECON CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |