Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26986682 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CSNK1DMAPK11MAPK14KMO | |
| SCHEMBL26986579 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAHPGDSMN1; SMN2 | |
| SCHEMBL30712646 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAHPGDSMN1; SMN2 | |
| SCHEMBL5223497 | 0.80 | SMN1; SMN2 (0.54) | ALDH1A1L3MBTL1KDM4EGAAHPGD | |
| SCHEMBL11657485 | 0.77 | DHODH (0.45) | ALDH1A1KMOLMNAKDM4EALOX15 | |
| SCHEMBL31146981 | 0.75 | SMARCA2 (0.61) | ALDH1A1CSNK1DMAPK11MAPK14TSHR | |
| SCHEMBL28241485 | 0.73 | DDT (0.55) | ALDH1A1KMOLMNANAPRTP4HTM | |
| SCHEMBL2837730 | 0.73 | KDM4E (0.54) | ALDH1A1KMOLMNANAPRTP4HTM | |
| SCHEMBL15761411 | 0.72 | ADORA2A (0.48) | ALDH1A1CSNK1DMAPK11MAPK14SOAT1 | |
| SCHEMBL1752937 | 0.72 | CSNK1D (0.47) | ALDH1A1CSNK1DMAPK11MAPK14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024009283-A1 | AT2 ANTAGONISTS FOR NON-ADDICTIVE PAIN RELIEF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-01-11 | — | — | WO | disclosed |