Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742187 | 0.85 | MPO (0.44) | MTNR1AMTNR1BNQO2BACE1ALDH1A1 | |
| SCHEMBL11659649 | 0.80 | KDM4E (0.37) | MTNR1AMTNR1BNQO2BACE1ALDH1A1 | |
| SCHEMBL11664913 | 0.78 | KMT2A (0.39) | BACE1ALDH1A1HPGDACHEMAPT | |
| SCHEMBL15874725 | 0.77 | MPO (0.55) | BACE1ALDH1A1GLAMETAP1MAPT | |
| SCHEMBL28756407 | 0.77 | CYP4F2 (0.36) | MTNR1AMTNR1BNQO2BACE1CYP3A4 | |
| SCHEMBL7633782 | 0.76 | ALDH1A1 (0.41) | BACE1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL1201997 | 0.75 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2ALDH1A1ACHE | |
| SCHEMBL17070937 | 0.73 | METAP1 (0.53) | MTNR1AMTNR1BBACE1ALDH1A1HPGD | |
| SCHEMBL7820683 | 0.73 | NQO2 (0.61) | MTNR1AMTNR1BNQO2ALDH1A1HPGD | |
| SCHEMBL18537152 | 0.72 | NQO2 (0.46) | MTNR1AMTNR1BNQO2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |