Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659649 | 0.81 | KDM4E (0.37) | CYP4F2CYP4A11NQO2MTNR1AMTNR1B | |
| SCHEMBL11659554 | 0.77 | MTNR1A (0.48) | NQO2MTNR1AMTNR1BBACE1CYP3A4 | |
| SCHEMBL7633782 | 0.73 | ALDH1A1 (0.41) | BACE1PTGS1 | |
| SCHEMBL28747226 | 0.72 | NOTUM (0.38) | CYP4F2CYP4A11BACE1CYP3A4 | |
| SCHEMBL15874888 | 0.67 | KDM4C (0.40) | CYP4F2CYP4A11BACE1 | |
| SCHEMBL25945070 | 0.65 | LMNA (0.40) | — | |
| SCHEMBL9199539 | 0.64 | NOTUM (0.39) | — | |
| SCHEMBL27742187 | 0.63 | MPO (0.44) | NQO2MTNR1AMTNR1BALOX5BACE1 | |
| SCHEMBL20651118 | 0.60 | METAP1 (0.33) | — | |
| SCHEMBL29448341 | 0.59 | PDGFRB (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1699335-A | Process for preparing sulindac | UNIV ZHEJIANG (CN) | 2005-11-23 | — | — | CN | disclosed |