Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.38 |
| ▸ | CCND1 | P24385 | 5/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.37 |
| ▸ | PRKCG | P05129 | 2/20 | 0.37 |
| ▸ | PRKCB | P05771 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17045729 | 0.81 | MAOA (0.44) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL6848266 | 0.77 | CDK4 (0.42) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL1889878 | 0.74 | PARP1 (0.55) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL1756365 | 0.74 | TRPM4 (0.48) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL339346 | 0.74 | GAA (0.41) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL3852137 | 0.74 | CDK4 (0.44) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL789452 | 0.72 | TRPM4 (0.47) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL1323425 | 0.72 | CASP6 (0.53) | GSK3BCDK2MAPTALDH1A1PARP1 | |
| SCHEMBL856132 | 0.71 | CDK4 (0.39) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL7767469 | 0.71 | MEN1 (0.50) | CDK4PRKCGPRKCBPRKCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998841-A | CHLOROTHIO-N-PHTHALIMIDE AND PROCESS THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | claimed |
| US-4080399-A | REACTING N-CHLOROTHIOPHTHALIMIDE WITH UNSATURATED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
| US-3998841-A | CHLOROTHIO-N-PHTHALIMIDE AND PROCESS THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |
| US-3998841-A | CHLOROTHIO-N-PHTHALIMIDE AND PROCESS THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |