Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | IL1RN | P18510 | 2/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663832 | 0.88 | ITGB3 (0.47) | PPARGIL1RNERAP2ERAP1ITGB3 | |
| SCHEMBL11663289 | 0.85 | MMP2 (0.48) | IL1RNERAP2ERAP1MAPTMAOB | |
| SCHEMBL11662219 | 0.81 | CTSL (0.53) | PPARGITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL11666177 | 0.80 | CTSS (0.47) | PPARGITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL14515253 | 0.78 | MAPT (0.55) | MAPTMAOBCRHBPCRHR2KCNH2 | |
| SCHEMBL11664047 | 0.78 | MAPT (0.55) | MAPTMAOBCRHBPCRHR2KCNH2 | |
| SCHEMBL14515255 | 0.78 | MAPT (0.55) | MAPTMAOBCRHBPCRHR2KCNH2 | |
| SCHEMBL11662218 | 0.76 | MEN1 (0.53) | MAPTMAOBMEN1KMT2AMMP2 | |
| SCHEMBL11664308 | 0.76 | MMP2 (0.64) | MAPTMAOBKCNH2MMP2CYP19A1 | |
| SCHEMBL11205081 | 0.76 | MEN1 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123614-A | USED IN DETECTION AND MEASUREMENT OF BIOLOGICAL SYSTEMS AND/OR COMPONENTS | SYNTEX (U.S.A.) INC. (US) | 1978-10-31 | — | — | US | disclosed |