Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504178 | 0.98 | IDO1 (0.64) | IDO1ALDH1A1POLBMLKLGAA | |
| SCHEMBL4921708 | 0.80 | IDO1 (1.00) | IDO1ALDH1A1POLBMLKLGAA | |
| SCHEMBL7946544 | 0.80 | IDO1 (0.78) | IDO1ALDH1A1POLBMLKLGAA | |
| SCHEMBL10636343 | 0.79 | ALDH1A1 (0.66) | IDO1ALDH1A1POLBMLKLGAA | |
| SCHEMBL1070187 | 0.79 | ALDH1A1 (0.56) | IDO1ALDH1A1POLBMLKLGAA | |
| SCHEMBL5798716 | 0.78 | KDM4E (0.55) | IDO1ALDH1A1POLBGAAL3MBTL1 | |
| SCHEMBL9214713 | 0.77 | ALDH1A1 (0.68) | IDO1ALDH1A1POLBMLKLGAA | |
| SCHEMBL8154223 | 0.77 | ALDH1A1 (0.53) | IDO1ALDH1A1POLBMLKLGAA | |
| SCHEMBL19425618 | 0.77 | IDO1 (0.85) | IDO1ALDH1A1POLBMLKLGAA | |
| SCHEMBL2673705 | 0.77 | IDO1 (0.72) | IDO1ALDH1A1POLBMLKLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119478-A | COLORLESS COMPOUND CONTAINING ONE OR MORE BASIC NITROGEN ATOMS ATTACHED TO CARBON IN PYRIDINE OR BENZIMIDAZOLE RING AND HAVING ONE OR MORE UREA OR URETHANE GROUPS | CIBA-GEIGY CORPORATION (US) | 1978-10-10 | — | — | US | claimed |