SCHEMBL8154223

SCHEMBL8154223

C=CC(c1ccccc1)c1nc2ccccc2[nH]1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
IDO1 P14902 1/20 0.53
POLB P06746 1/20 0.53
ALPL P05186 1/20 0.48
MAPK1 P28482 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
MLKL Q8NB16 3/20 0.47
GAA P10253 2/20 0.46
KMT2A Q03164 5/20 0.45
KDM4E B2RXH2 3/20 0.43
HPGD P15428 2/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
PKM P14618 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
ABCB11 O95342 1/20 0.43
TP53 P04637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1349930 0.78 ALDH1A1 (0.61) ALDH1A1IDO1POLBALPLMAPK1
SCHEMBL10636343 0.77 ALDH1A1 (0.66) ALDH1A1IDO1POLBMAPK1TAAR1
SCHEMBL1070187 0.77 ALDH1A1 (0.56) ALDH1A1IDO1POLBALPLMAPK1
SCHEMBL11663293 0.77 IDO1 (0.66) ALDH1A1IDO1POLBTAAR1MLKL
SCHEMBL8504178 0.75 IDO1 (0.64) ALDH1A1IDO1POLBTAAR1MLKL
SCHEMBL9214713 0.75 ALDH1A1 (0.68) ALDH1A1IDO1POLBTAAR1MLKL
SCHEMBL899731 0.75 MLKL (0.77) ALDH1A1IDO1POLBALPLMAPK1
SCHEMBL16756243 0.75 ALPL (0.58) ALDH1A1IDO1POLBALPLMAPK1
SCHEMBL3397595 0.75 ALPL (0.58) ALDH1A1IDO1POLBALPLMAPK1
SCHEMBL11807688 0.75 ALDH1A1 (0.58) ALDH1A1IDO1POLBALPLMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6002158-A None JP disclosed
US-6158491-A Process for the corrosion protection of copper or copper alloys COOKSON GROUP PLC (GB) 2000-12-12 US disclosed
EP-0799327-B1 PROCESS FOR THE CORROSION PROTECTION OF COPPER OR COPPER ALLOYS COOKSON GROUP PLC (GB) 1999-04-14 EP disclosed
EP-0799327-A1 PROCESS FOR THE CORROSION PROTECTION OF COPPER OR COPPER ALLOYS COOKSON GROUP plc (GB) 1997-10-08 EP disclosed
WO-1996020295-A1 PROCESS FOR THE CORROSION PROTECTION OF COPPER OR COPPER ALLOYS COOKSON GROUP PLC (GB) 1996-07-04 WO disclosed
EP-0551112-B1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO LTD (JP) 1996-04-03 EP disclosed
US-5476947-A Excellent rust preventing effect, useful as corrosion resistance protective coating in printed wiring boards MEC CO., LTD. (JP) 1995-12-19 US disclosed
US-5435860-A Corrosion resistance for printed circuits MEC CO., LTD. (JP) 1995-07-25 US disclosed
JP-H062158-A SURFACE TREATING AGENT OF COPPER AND COPPER ALLOY SHIKOKU CHEM CORP 1994-01-11 JP disclosed
EP-0551112-A1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO., Ltd. (JP) 1993-07-14 EP disclosed
US-4987145-A Acaricidal or insecticidal substituted 1-phenylalkyl benzimidazole compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-22 US disclosed
US-4663339-A Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-05 US disclosed