Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11664314 | 0.83 | TAAR1 (0.34) | CASRMAOBIDO1AGXTAOC3 | |
| SCHEMBL11662206 | 0.83 | TRPA1 (0.47) | CASRMAOBTRPA1 | |
| SCHEMBL11616522 | 0.76 | TRPA1 (0.40) | CASRIDO1TRPA1LOXL2HPGD | |
| SCHEMBL11665566 | 0.75 | NFE2L2 (0.34) | CASRMAOBAOC3 | |
| SCHEMBL11663075 | 0.73 | CASR (0.35) | CASRMAOBIDO1AGXTAOC3 | |
| SCHEMBL11662016 | 0.73 | HTR2A (0.47) | MAOBIDO1SIGMAR1 | |
| SCHEMBL14349290 | 0.72 | TRPA1 (0.42) | CASRMAOBIDO1AGXTTRPA1 | |
| SCHEMBL11612653 | 0.69 | IDO1 (0.37) | IDO1AGXTAOC3TRPA1LOXL2 | |
| SCHEMBL5447904 | 0.69 | TRPA1 (0.47) | CASRMAOBIDO1TRPA1LOXL2 | |
| SCHEMBL11661922 | 0.68 | TSHR (0.39) | TRPA1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |