Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661922 | 0.85 | TSHR (0.39) | TAAR1TRPA1NR3C1TSHRKMT2A | |
| SCHEMBL11665133 | 0.83 | CASR (0.35) | CASRIDO1AGXTAOC3TRPA1 | |
| SCHEMBL11517084 | 0.74 | CASR (0.35) | TAAR1CASRIDO1AGXTTRPA1 | |
| SCHEMBL11659218 | 0.72 | TAAR1 (0.33) | TAAR1CASRIDO1AGXTAOC3 | |
| SCHEMBL11665566 | 0.71 | NFE2L2 (0.34) | CASRAOC3MAOBGAAKDM4E | |
| SCHEMBL11662591 | 0.66 | L3MBTL1 (0.44) | TAAR1IDO1AGXTAOC3MAOB | |
| SCHEMBL11662206 | 0.66 | TRPA1 (0.47) | TAAR1CASRTRPA1MAOBKMT2A | |
| SCHEMBL11616522 | 0.66 | TRPA1 (0.40) | CASRIDO1TRPA1LOXL2KDM4E | |
| SCHEMBL10248786 | 0.65 | IDO1 (0.48) | TAAR1IDO1AGXTAOC3LOXL2 | |
| SCHEMBL28226140 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |