Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281920 | 0.87 | KDM4E (0.49) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL30167649 | 0.79 | L3MBTL1 (0.55) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL11664066 | 0.79 | WDR5 (0.46) | KDM4EMAOBAOC3LMNAPKM | |
| SCHEMBL14227148 | 0.78 | L3MBTL1 (0.52) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL14241271 | 0.78 | L3MBTL1 (0.52) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL11662719 | 0.78 | MAOB (0.49) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL535459 | 0.77 | L3MBTL1 (0.54) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL11665128 | 0.77 | LMNA (0.41) | ALDH1A1LMNA | |
| SCHEMBL11663126 | 0.77 | KDM4E (0.42) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL72484 | 0.74 | L3MBTL1 (0.59) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |