Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285190 | 0.82 | HDAC3 (0.42) | LMNAALDH1A1RECQLKDM1AKCNA3 | |
| SCHEMBL10968500 | 0.82 | LTA4H (0.44) | LMNAALDH1A1RECQLKDM1AKCNA3 | |
| SCHEMBL29364033 | 0.82 | ALDH1A1 (0.47) | LMNAALDH1A1RECQLKDM1AKCNA3 | |
| SCHEMBL11665744 | 0.81 | SSTR4 (0.40) | CYP2D6SSTR4CYP2C19 | |
| SCHEMBL10516249 | 0.80 | MAPT (0.49) | LMNAALDH1A1RECQLKDM1AKCNA3 | |
| SCHEMBL11664066 | 0.80 | WDR5 (0.46) | LMNACYP2D6 | |
| SCHEMBL97005 | 0.79 | LMNA (0.47) | LMNAALDH1A1RECQLKCNA3CYP2D6 | |
| SCHEMBL27276974 | 0.79 | LMNA (0.47) | LMNAALDH1A1RECQLKCNA3CYP2D6 | |
| SCHEMBL11465579 | 0.79 | ALDH1A1 (0.48) | LMNAALDH1A1RECQLKDM1AKCNA3 | |
| SCHEMBL11095913 | 0.78 | LMNA (0.45) | LMNAALDH1A1RECQLKCNA3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |