SCHEMBL11665205

SCHEMBL11665205

CCOC(=O)Cc1cccc(N=C=S)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 1/20 0.47
CYP4Z1 Q86W10 1/20 0.43
MAOB P27338 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
NPC1 O15118 1/20 0.40
PKM P14618 1/20 0.40
NFKB1 P19838 1/20 0.40
RAB9A P51151 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 4/20 0.39
MAPT P10636 3/20 0.39
MEN1 O00255 3/20 0.39
CYP3A4 P08684 2/20 0.39
TP53 P04637 1/20 0.39
RECQL P46063 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
F10 P00742 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11626840 0.87 CYP4Z1 (0.44) CYP4Z1MAOBSMN1; SMN2L3MBTL1NPC1
SCHEMBL11627635 0.86 SLC7A5 (0.48) OPRD1SMN1; SMN2NPC1PKMNFKB1
SCHEMBL3765043 0.82 CYP4Z1 (0.57) OPRD1CYP4Z1SMN1; SMN2ALDH1A1KMT2A
SCHEMBL11627720 0.82 TSHR (0.55) OPRD1SMN1; SMN2ALDH1A1KMT2AMAPT
SCHEMBL68412 0.80 L3MBTL1 (0.50) CYP4Z1MAOBSMN1; SMN2L3MBTL1NPC1
SCHEMBL11630471 0.79 OPRD1 (0.49) OPRD1NFKB1ALDH1A1KMT2AMAPT
Hydrochloric Acid SCHEMBL11628256 0.78 OPRD1 (0.48) OPRD1SMN1; SMN2NFKB1ALDH1A1KMT2A
SCHEMBL11628252 0.78 OPRD1 (0.46) OPRD1SMN1; SMN2ALDH1A1KMT2AMAPT
SCHEMBL5558418 0.77 CYP4F2 (0.49) SMN1; SMN2NPC1RAB9AALDH1A1KMT2A
SCHEMBL406058 0.76 MAOB (0.58) MAOBSMN1; SMN2ALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4067726-A 3-Ureido phenylacetamide herbicides BAYER AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed