Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30427003 | 0.87 | CYP4F2 (0.50) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL445504 | 0.87 | CYP4F2 (0.50) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7393239 | 0.84 | CA12 (0.51) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29754225 | 0.83 | ALDH1A1 (0.48) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1421363 | 0.83 | ALDH1A1 (0.48) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23191916 | 0.82 | TDP1 (0.58) | NPC1RAB9ASMN1; SMN2CYP2C9HPGD | |
| SCHEMBL1457515 | 0.81 | MAPT (0.56) | NPC1RAB9ASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL14257225 | 0.81 | CYP4F2 (0.54) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6070567 | 0.80 | MAPT (0.58) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12644215 | 0.80 | CYP4F2 (0.52) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
| WO-2005027856-A2 | INHIBITORS OF ANTHRAX LETHAL FACTOR | CENGENT THERAPEUTICS (US) | 2005-03-31 | — | — | WO | disclosed |
| EP-0117511-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-09-20 | — | — | EP | disclosed |
| US-4737452-A | WITH AROMATIC COMPOUND CONTAINING MERCAPTO AND HYDROZIDE GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| US-4628024-A | RELEASING A FOGGING AGENT; CONTRAST; STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1986-12-09 | — | — | US | disclosed |
| US-4550070-A | Direct positive silver halide photographic light-sensitive materials | FUJI PHOTO FILM CO., LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| EP-0154293-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1985-09-11 | — | — | EP | disclosed |
| EP-0147765-A2 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-07-10 | — | — | EP | disclosed |
| EP-0117511-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | CYP4F2 1720/4885CYP4A11 3265/4885NPC1 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.