Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989562 | 0.95 | ALDH1A1 (0.36) | HPGDSMN1; SMN2ALDH1A1TSHRNPC1 | |
| SCHEMBL9287586 | 0.89 | ALDH1A1 (0.36) | HPGDSMN1; SMN2ALDH1A1TSHRTHRB | |
| SCHEMBL4939652 | 0.85 | ALDH1A1 (0.42) | HPGDALDH1A1TSHRKMT2A | |
| SCHEMBL11648809 | 0.81 | ALDH1A1 (0.36) | HPGDSMN1; SMN2ALDH1A1TSHRNPC1 | |
| SCHEMBL7714477 | 0.81 | CES1 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL2304429 | 0.79 | KMT2A (0.45) | ALDH1A1TSHRKMT2A | |
| SCHEMBL2302039 | 0.78 | KMT2A (0.48) | ALDH1A1TSHRKMT2A | |
| SCHEMBL7950973 | 0.78 | KMT2A (0.48) | ALDH1A1TSHRKMT2A | |
| SCHEMBL11623313 | 0.78 | KMT2A (0.48) | ALDH1A1TSHRKMT2A | |
| SCHEMBL7563843 | 0.78 | KMT2A (0.48) | ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094899-A | Oxaprostaglandins | PFIZER INC. (US) | 1978-06-13 | — | — | US | disclosed |