Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304429 | 0.94 | KMT2A (0.45) | CES1CES2ALDH1A1MAPTKMT2A | |
| SCHEMBL7947906 | 0.92 | KMT2A (0.48) | CES1CES2ALDH1A1MAPTKMT2A | |
| SCHEMBL11623313 | 0.92 | KMT2A (0.48) | CES1CES2ALDH1A1MAPTKMT2A | |
| SCHEMBL7950973 | 0.92 | KMT2A (0.48) | CES1CES2ALDH1A1MAPTKMT2A | |
| SCHEMBL11626606 | 0.92 | KMT2A (0.48) | CES1CES2ALDH1A1MAPTKMT2A | |
| SCHEMBL7563843 | 0.92 | KMT2A (0.48) | CES1CES2ALDH1A1MAPTKMT2A | |
| SCHEMBL2302039 | 0.92 | KMT2A (0.48) | CES1CES2ALDH1A1MAPTKMT2A | |
| SCHEMBL10826323 | 0.87 | LMNA (0.38) | CES1CES2ALDH1A1 | |
| SCHEMBL17673047 | 0.86 | TSHR (0.45) | ALDH1A1MAPTKMT2AHAO1CA12 | |
| SCHEMBL4939652 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161381-A | Hydrophobic monomer and preparation method thereof, polymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-12-20 | — | — | CN | disclosed |
| US-6376480-B1 | TREATMENT OF IMMUNE SYSTEM DISORDERS, OSTEOPOROSIS, ALOPECIA | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-23 | — | — | US | disclosed |
| US-6372731-B1 | TREATMENT OF CELL PROLIFERATION AND BONE DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-16 | — | — | US | disclosed |
| EP-0832063-B1 | VITAMIN D DERIVATIVES WITH C-25 SUBSTITUENTS, PROCESS FOR THEIR PREPARATION, INTERMEDIATE PRODUCTS AND THEIR USE IN PREPARING MEDICAMENTS | SCHERING AG (DE) | 2000-02-23 | — | — | EP | disclosed |
| EP-0832063-A1 | NOVEL VITAMIN D DERIVATIVES WITH C-25 SUBSTITUENTS, PROCESS FOR THEIR PREPARATION, INTERMEDIATE PRODUCTS AND THEIR USE IN PREPARING MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997000242-A1 | NOVEL VITAMIN D DERIVATIVES WITH C-25 SUBSTITUENTS, PROCESS FOR THEIR PREPARATION, INTERMEDIATE PRODUCTS AND THEIR USE IN PREPARING MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-01-03 | — | — | WO | disclosed |
| US-4618627-A | ALLERGIES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0125919-A2 | Catechol derivatives, their production and intermediates therefor, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-11-21 | — | — | EP | disclosed |
| US-4113873-A | 8-AZAPROSTANOIC ACID DERIVATIVES | TANABE SEIYAKU CO. LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-3987072-A | CIS-4,5-Didehydro-15- or 16-alkylated 11-deoxy-PGE1 analogs | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3970684-A | Polyunsaturated prostaglandin derivatives | SYNTEX (U.S.A.) INC. (US) | 1976-07-20 | — | — | US | disclosed |