Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623313 | 0.98 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7950973 | 0.98 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL2302039 | 0.98 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL11626606 | 0.98 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7563843 | 0.98 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7947906 | 0.98 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7714477 | 0.94 | CES1 (0.41) | KMT2AMAPTCES2CES1AKR1B1 | |
| SCHEMBL17673047 | 0.91 | TSHR (0.45) | KMT2AMAPTHAO1TSHRALDH1A1 | |
| SCHEMBL28191042 | 0.86 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL10826323 | 0.85 | LMNA (0.38) | CES2CES1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400793-A1 | COMPOSITION FOR POLYURETHANE FOAM, FOAM PREPARED THEREFROM AND A METHOD THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2024-12-05 | — | — | US | claimed |
| EP-4396271-A1 | COMPOSITION FOR POLYURETHANE FOAM, FOAM PREPARED THEREFROM AND A METHOD THEREOF | Momentive Performance Materials Inc. (US) | 2024-07-10 | — | — | EP | claimed |
| WO-2023034354-A1 | COMPOSITION FOR POLYURETHANE FOAM, FOAM PREPARED THEREFROM AND A METHOD THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2023-03-09 | — | — | WO | claimed |
| CN-112979599-A | Preparation method of carboprost tromethamine intermediate | 河北赛谱睿思医药科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| EP-0144459-A1 | Prostaglandins, their preparation and pharmaceutical compositions | Dr. Willmar Schwabe GmbH & Co. (DE) | 1985-06-19 | — | — | EP | claimed |
| EP-0113561-A2 | Prostaglandin intermediates, their synthesis and their conversion to prostaglandins | THE UPJOHN COMPANY (US) | 1984-07-18 | — | — | EP | claimed |
| US-4176122-A | Process for the preparation of bicyclic enone compounds | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK (HU) | 1979-11-27 | — | — | US | claimed |
| US-4052407-A | ENZYME INHIBITORS, MULTISTAGE | GYOGYSZERKUTATO INTEZET (HU) | 1977-10-04 | — | — | US | claimed |
| US-3992439-A | ESTERIFICATION, ACYLATION, HYDROGENATION, OXIDATION, HYDROLYZING | PFIZER INC. (US) | 1976-11-16 | — | — | US | claimed |
| JP-63216866-A | — | — | None | — | — | JP | disclosed |
| US-20240400793-A1 | COMPOSITION FOR POLYURETHANE FOAM, FOAM PREPARED THEREFROM AND A METHOD THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2024-12-05 | — | — | US | disclosed |
| WO-2024190777-A1 | TRICYCLIC COMPOUND | 小野薬品工業株式会社 | 2024-09-19 | — | — | WO | disclosed |
| WO-2024190780-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR KIDNEY DISEASES CONTAINING TRICYCLIC COMPOUND | 小野薬品工業株式会社 | 2024-09-19 | — | — | WO | disclosed |
| US-20240287105-A1 | TREPROSTINIL ANALOGS AND RELATED METHODS OF MAKING AND USING | UNITED THERAPEUTICS CORPORATION (US) | 2024-08-29 | — | — | US | disclosed |
| US-3950359-A | PROSTAGLANDINS AND METHODS OF MAKING SAME | MERCK & CO., INC. (US) | 1976-04-13 | — | — | US | disclosed |
| US-3947469-A | PROSTAGLANDIN INTERMEDIATES | RECHERCHE ET INDUSTRIE THERAPEUTIQUES (R.I.T.) (BE) | 1976-03-30 | — | — | US | disclosed |
| US-3939182-A | Prostaglandin E1 intermediate 6α-carboxy-5α(1-hydroxyethyl)-2-cyclohexene-1-heptanoic acid,γ-lactone, and lower alkyl or aralkyl esters thereof | MERCK & CO., INC. (US) | 1976-02-17 | — | — | US | disclosed |
| US-3935254-A | 5C-PROSTEN-13-YNOIC ACIDS | CARLO ERBA S.P.A. (IT) | 1976-01-27 | — | — | US | disclosed |
| US-3931297-A | 10-Hydroxy PGC compounds | SYNTEX (U.S.A.) INC. (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287105-A1 | TREPROSTINIL ANALOGS AND RELATED METHODS OF MAKING AND USING | TYMP, TTPA, PTGIS | KMT2A 3470/4885MAPT 3498/4885CES2 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.