Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598756 | 0.89 | ALDH1A1 (0.55) | MAPTRAB9ASMN1; SMN2GAANPC1 | |
| SCHEMBL11771377 | 0.88 | ALDH1A1 (0.57) | MAPTNPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11657310 | 0.88 | POLB (0.56) | MAPTRAB9AGAAHTTNPC1 | |
| SCHEMBL11775723 | 0.86 | KDM4E (0.60) | MAPTGAANPC1ALDH1A1KMT2A | |
| SCHEMBL11773236 | 0.86 | KDM4E (0.66) | MAPTRAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL5158239 | 0.85 | MAPT (0.59) | MAPTRAB9ASMN1; SMN2GAAHTT | |
| SCHEMBL11624948 | 0.84 | ALDH1A1 (0.51) | MAPTRAB9ASMN1; SMN2HTTMAOB | |
| SCHEMBL11770628 | 0.84 | NPC1 (0.53) | MAPTRAB9ASMN1; SMN2GAAHTT | |
| SCHEMBL13300455 | 0.83 | MEN1 (0.59) | MAPTRAB9ASMN1; SMN2GAAHTT | |
| SCHEMBL12305614 | 0.82 | MAPT (0.58) | MAPTRAB9ASMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096157-A | PIGMENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-3939194-A | Bis-2-azomethine pigments, process for their manufacture and their use | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |