Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662821 | 0.87 | NPC1 (0.52) | NPC1RAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL11624948 | 0.87 | ALDH1A1 (0.51) | NPC1RAB9ACYP2C9CYP1A2CYP2C19 | |
| SCHEMBL11598294 | 0.87 | PPARG (0.45) | NPC1RAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL11776026 | 0.85 | MAPT (0.49) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7539667 | 0.84 | NPC1 (0.53) | NPC1RAB9ACYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11665696 | 0.84 | MAPT (0.55) | NPC1RAB9AHSD17B10GAAMEN1 | |
| SCHEMBL10522985 | 0.84 | HTT (0.64) | NPC1RAB9ACYP3A4HSD17B10GAA | |
| SCHEMBL11660033 | 0.83 | HTT (0.56) | MEN1KMT2AALDH1A1HTTLMNA | |
| SCHEMBL11664267 | 0.82 | RAB9A (0.52) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL11659997 | 0.82 | MAOA (0.54) | NPC1RAB9AHSD17B10GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939194-A | Bis-2-azomethine pigments, process for their manufacture and their use | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |