Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MPL | P40238 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863351 | 0.80 | TTR (0.42) | MEN1KMT2AMPLPOLBCYP1A2 | |
| SCHEMBL9229519 | 0.79 | MEN1 (0.51) | MEN1KMT2APOLBGABRA1GABRB2 | |
| SCHEMBL14977703 | 0.78 | TTR (0.41) | MEN1KMT2AMPLPOLBCYP1A2 | |
| SCHEMBL24922445 | 0.77 | MEN1 (0.50) | MEN1KMT2APOLBGABRA1GABRB2 | |
| SCHEMBL11666020 | 0.77 | CYP2D6 (0.50) | MEN1KMT2AMPLPOLBGABRA1 | |
| SCHEMBL6548552 | 0.75 | GABRA1 (0.44) | MEN1KMT2APOLBGABRA1GABRB2 | |
| SCHEMBL30700 | 0.75 | GABRA1 (0.44) | MEN1KMT2APOLBGABRA1GABRB2 | |
| SCHEMBL7538465 | 0.75 | MPL (0.58) | MEN1KMT2AMPLCYP1A2CYP2D6 | |
| SCHEMBL8658348 | 0.74 | GABRA1 (0.58) | MEN1KMT2APOLBCYP1A2GABRA1 | |
| SCHEMBL3291895 | 0.74 | MEN1 (0.48) | MEN1KMT2APOLBCYP1A2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4120897-A | 2-Alkyl-1-naphthol-4-sulfonic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-4110473-A | MITICIDAL ETHERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4049705-A | 2-Alkyl-1-naphthol-4-sulfonic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-09-20 | — | — | US | disclosed |