SCHEMBL7863351

SCHEMBL7863351

C=CCc1ccc(S(=O)(=O)O)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.42
CYP1A2 P05177 3/20 0.40
CTRB1 P17538 1/20 0.39
POLB P06746 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
COMT P21964 1/20 0.37
AURKA O14965 1/20 0.37
AURKB Q96GD4 1/20 0.37
TNNI3 P19429 1/20 0.36
TNNT2 P45379 1/20 0.36
TNNC1 P63316 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
LDHA P00338 1/20 0.36
MPL P40238 2/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14977703 0.98 TTR (0.41) TTRCYP1A2CTRB1POLBMEN1
SCHEMBL14977704 0.82 THRB (0.41) POLBMEN1KMT2AGABRA1GABRB2
SCHEMBL28419110 0.80 TTR (0.48) TTRCYP1A2CTRB1MEN1KMT2A
SCHEMBL5831736 0.80 GABRA1 (0.45) POLBMEN1KMT2AAURKAAURKB
SCHEMBL11667635 0.80 MEN1 (0.50) CYP1A2POLBMEN1KMT2AGABRA1
SCHEMBL7791002 0.79 TTR (0.47) TTRCYP1A2CTRB1COMTAURKA
SCHEMBL30700 0.79 GABRA1 (0.44) TTRPOLBMEN1KMT2AGABRA1
SCHEMBL6548552 0.79 GABRA1 (0.44) TTRPOLBMEN1KMT2AGABRA1
SCHEMBL9604893 0.78 CA2 (0.44) TTRCYP1A2CTRB1MEN1KMT2A
SCHEMBL29409575 0.78 TTR (0.61) TTRCYP1A2CTRB1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1100329-A1 AQUEOUS GROWTH-REGULATING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2001-05-23 EP disclosed
WO-2000007445-A1 AQUEOUS GROWTH-REGULATING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2000-02-17 WO disclosed