Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.35 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863351 | 0.98 | TTR (0.42) | TTRCYP1A2CTRB1MEN1KMT2A | |
| SCHEMBL14977704 | 0.81 | THRB (0.41) | MEN1KMT2APOLBGABRA1GABRB2 | |
| SCHEMBL553258 | 0.80 | GABRA1 (0.43) | TTRMEN1KMT2APOLBGABRA1 | |
| SCHEMBL28419110 | 0.79 | TTR (0.48) | TTRCYP1A2CTRB1MEN1KMT2A | |
| SCHEMBL7710380 | 0.78 | TTR (0.59) | TTRCYP1A2CTRB1MEN1KMT2A | |
| SCHEMBL5831736 | 0.78 | GABRA1 (0.45) | MEN1KMT2APOLBAURKAAURKB | |
| SCHEMBL11667635 | 0.78 | MEN1 (0.50) | CYP1A2MEN1KMT2APOLBGABRA1 | |
| SCHEMBL7791002 | 0.78 | TTR (0.47) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL30700 | 0.78 | GABRA1 (0.44) | TTRMEN1KMT2APOLBGABRA1 | |
| SCHEMBL6548552 | 0.78 | GABRA1 (0.44) | TTRMEN1KMT2APOLBGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759553-B1 | METHOD FOR PRODUCING NITRILE RUBBER | LG CHEMICAL LTD (KR) | 2017-05-31 | — | — | EP | disclosed |
| US-9163096-B2 | Method for producing nitrile rubber | LG CHEM, LTD. (KR) | 2015-10-20 | — | — | US | disclosed |
| US-20140350203-A1 | METHOD FOR PRODUCING NITRILE RUBBER | LG CHEM, LTD. (KR) | 2014-11-27 | — | — | US | disclosed |
| EP-2759553-A1 | PRODUCTION METHOD FOR NITRILE RUBBER | LG Chem, Ltd. (KR) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013077530-A1 | PRODUCTION METHOD FOR NITRILE RUBBER | (주) 엘지화학 (KR) | 2013-05-30 | — | — | WO | disclosed |