Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668909 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KMT2AKDM4ETSHRMEN1 | |
| SCHEMBL8613202 | 0.81 | KDM4E (0.63) | ALDH1A1KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL31140889 | 0.78 | PARP1 (0.46) | ELANE | |
| SCHEMBL7811084 | 0.78 | PARP1 (0.46) | ELANE | |
| SCHEMBL57542 | 0.77 | KDM4E (0.69) | ALDH1A1KMT2AKDM4EMEN1RXFP1 | |
| SCHEMBL9768818 | 0.76 | DHODH (0.47) | ALDH1A1KMT2AKDM4ETSHRMEN1 | |
| Hydrochloric Acid SCHEMBL31715997 | 0.76 | KDM4E (0.67) | ALDH1A1KMT2AKDM4EMEN1RXFP1 | |
| SCHEMBL11669054 | 0.75 | TSHR (0.47) | ALDH1A1KMT2AKDM4ETSHRMEN1 | |
| SCHEMBL5664709 | 0.72 | ALDH1A1 (0.70) | ALDH1A1KMT2AKDM4ETSHRMEN1 | |
| SCHEMBL7524860 | 0.72 | KDM4E (0.44) | ALDH1A1KMT2AKDM4ETSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009020-A | QUINOLINE-4-CARBOXYLIC ACID OR SALTS | AMCHEM PRODUCTS, INC. (US) | 1977-02-22 | — | — | US | disclosed |