Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668917 | 0.83 | LMNA (0.49) | SMN1; SMN2LMNANPC1RAB9AKMT2A | |
| SCHEMBL4449787 | 0.78 | LMNA (0.50) | SMN1; SMN2LMNANPC1RAB9AKMT2A | |
| SCHEMBL9376853 | 0.73 | MAPT (0.36) | SMN1; SMN2LMNAHTTNPSR1NPC1 | |
| SCHEMBL9824016 | 0.71 | ALDH1A1 (0.38) | SMN1; SMN2LMNANPSR1RAB9AKMT2A | |
| SCHEMBL10671305 | 0.68 | KMT2A (0.62) | SMN1; SMN2HTTPOLBNPC1RAB9A | |
| SCHEMBL9419236 | 0.67 | RAB9A (0.35) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL6109583 | 0.67 | POLB (0.59) | SMN1; SMN2LMNANPSR1CYP2C19POLB | |
| SCHEMBL14119932 | 0.67 | LMNA (1.00) | SMN1; SMN2LMNAHTTNPSR1POLB | |
| SCHEMBL11360021 | 0.67 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHTTNPSR1CYP2C19 | |
| SCHEMBL316088 | 0.67 | POLB (0.60) | SMN1; SMN2LMNAHTTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33745-E | Thiadiazabicyclononane derivatives, processes for their production and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0238711-B1 | THIADIAZABICYCLONONANE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND HERBIZIDAL COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |
| US-4816063-A | PLANT GROWTH REGULATORS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-03-28 | — | — | US | disclosed |
| EP-0238711-A1 | Thiadiazabicyclononane derivatives, processes for their production and herbizidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |
| US-4249934-A | 1,2-Alkylene-4-substituted urazole herbicides | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |