Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790031 | 0.82 | TSHR (0.52) | TSHRALDH1A1MEN1KMT2ATAAR1 | |
| SCHEMBL8629960 | 0.79 | ALOX5 (0.42) | TSHRALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11669014 | 0.77 | ALOX5 (0.46) | TSHRALDH1A1MEN1KMT2ARIPK1 | |
| SCHEMBL13990259 | 0.77 | TSHR (0.41) | TSHRALDH1A1MEN1KMT2APOLB | |
| SCHEMBL14641064 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1642904 | 0.75 | HTT (0.50) | ALDH1A1POLBRIPK1ALOX5MAPT | |
| SCHEMBL2806112 | 0.75 | HTT (0.50) | ALDH1A1POLBRIPK1ALOX5MAPT | |
| SCHEMBL8633566 | 0.74 | TSHR (0.55) | TSHRCNR2ALDH1A1MEN1KMT2A | |
| Diethylaniline SCHEMBL9000098 | 0.73 | TSHR (0.70) | TSHRCNR2ALDH1A1MEN1KMT2A | |
| Diethylaniline SCHEMBL17594 | 0.73 | TSHR (0.70) | TSHRCNR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |