Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLQ | O75417 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GPX4 | P36969 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671665 | 0.93 | GAA (0.46) | ALDH1A1MAPTTP53HTTKDM4E | |
| SCHEMBL11671871 | 0.93 | MAPT (0.42) | HSD17B1HSD17B2ALDH1A1MAPTTP53 | |
| SCHEMBL11670409 | 0.92 | LMNA (0.40) | HSD17B1HSD17B2ALDH1A1MAPTTP53 | |
| SCHEMBL11671621 | 0.92 | POLB (0.40) | HSD17B1HSD17B2ALDH1A1MAPTTP53 | |
| SCHEMBL11671693 | 0.91 | LMNA (0.46) | HSD17B1HSD17B2ALDH1A1MAPTTP53 | |
| SCHEMBL11672045 | 0.91 | PPARG (0.42) | HSD17B1HSD17B2MAPTTP53GAA | |
| SCHEMBL11670716 | 0.90 | POLQ (0.38) | HSD17B1HSD17B2ALDH1A1MAPTTP53 | |
| SCHEMBL11671423 | 0.90 | MEN1 (0.42) | HSD17B1HSD17B2ALDH1A1MAPTTP53 | |
| SCHEMBL11672314 | 0.90 | S1PR1 (0.41) | ALDH1A1MAPTTP53GAAKMT2A | |
| SCHEMBL11670324 | 0.90 | MTNR1B (0.44) | HSD17B1HSD17B2ALDH1A1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039526-A | PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4039539-A | 1,2,4-Triazole-azo-aniline cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |