Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671871 | 0.93 | MAPT (0.42) | MAPTTP53HSD17B1HSD17B2NPC1 | |
| SCHEMBL11670507 | 0.91 | HSD17B1 (0.43) | MAPTTP53HSD17B1HSD17B2NPC1 | |
| SCHEMBL11702436 | 0.90 | MAPT (0.44) | LTB4R2MAPTNPC1RAB9ACYP1A2 | |
| SCHEMBL11670807 | 0.89 | RAB9A (0.42) | PPARGPPARALTB4R2MAPTTP53 | |
| SCHEMBL11671665 | 0.89 | GAA (0.46) | MAPTTP53NPC1RAB9AGAA | |
| SCHEMBL11672996 | 0.88 | S1PR1 (0.39) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL11672792 | 0.88 | MTNR1B (0.48) | HSD17B1HSD17B2ALOX5 | |
| SCHEMBL11671621 | 0.88 | POLB (0.40) | PPARGLTB4R2MAPTTP53HSD17B1 | |
| SCHEMBL11670409 | 0.88 | LMNA (0.40) | MAPTTP53HSD17B1HSD17B2POLB | |
| SCHEMBL11671693 | 0.87 | LMNA (0.46) | MAPTTP53HSD17B1HSD17B2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039526-A | PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4039539-A | 1,2,4-Triazole-azo-aniline cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |