Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670507 | 0.93 | HSD17B1 (0.43) | GAANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL11670162 | 0.91 | MTNR1B (0.48) | MTNR1AMTNR1B | |
| SCHEMBL11671871 | 0.91 | MAPT (0.42) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL11671621 | 0.90 | POLB (0.40) | GAANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL11670409 | 0.90 | LMNA (0.40) | ALDH1A1KDM4EMAPTHTTMEN1 | |
| SCHEMBL11670567 | 0.90 | MTNR1B (0.44) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL11670324 | 0.90 | MTNR1B (0.44) | GAAALDH1A1MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL11671693 | 0.89 | LMNA (0.46) | GAAALDH1A1KDM4EMAPTHTT | |
| SCHEMBL11672045 | 0.89 | PPARG (0.42) | GAANPC1RAB9AMAPTTP53 | |
| SCHEMBL11670716 | 0.88 | POLQ (0.38) | ALDH1A1KDM4EMAPTHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039526-A | PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4039539-A | 1,2,4-Triazole-azo-aniline cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |