Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595452 | 0.77 | ALDH1A1 (0.46) | ACLYALDH1A1MAPTL3MBTL1TSHR | |
| SCHEMBL8910908 | 0.72 | VCAM1 (0.50) | VCAM1ALDH1A1NPSR1PSEN1PSEN2 | |
| SCHEMBL11595168 | 0.72 | TSHR (0.52) | SMN1; SMN2POLBACLYALDH1A1KMT2A | |
| SCHEMBL11740334 | 0.72 | ACLY (0.48) | VCAM1ACLYTHRB | |
| SCHEMBL9305533 | 0.71 | HTT (0.54) | VCAM1SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL10687962 | 0.71 | ALDH1A1 (0.47) | VCAM1SMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL11670822 | 0.70 | VCAM1 (0.45) | VCAM1SMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL199133 | 0.69 | PSEN1 (0.43) | VCAM1SMN1; SMN2POLBALDH1A1PSEN1 | |
| SCHEMBL9520453 | 0.69 | CTRC (0.37) | POLBACLYALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11742822 | 0.69 | THRB (0.46) | VCAM1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |