Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14065427 | 0.88 | TDP1 (0.61) | NR1I2TDP1MAPTHSD17B10CYP3A4 | |
| SCHEMBL11695289 | 0.86 | NR1I2 (0.47) | CA5ANR1I2TDP1MAPTHSD17B10 | |
| SCHEMBL9477095 | 0.85 | CTDSP1 (0.55) | NR1I2TDP1MAPTHSD17B10CYP3A4 | |
| SCHEMBL9477097 | 0.85 | CTDSP1 (0.55) | NR1I2TDP1MAPTHSD17B10CYP3A4 | |
| SCHEMBL8771113 | 0.85 | NR1I2 (0.49) | CA5ANR1I2TDP1MAPTHSD17B10 | |
| SCHEMBL8771118 | 0.85 | NR1I2 (0.49) | CA5ANR1I2TDP1MAPTHSD17B10 | |
| SCHEMBL14065430 | 0.84 | TDP1 (0.62) | NR1I2TDP1MAPTHSD17B10CYP3A4 | |
| SCHEMBL11674593 | 0.84 | TDP1 (0.62) | NR1I2TDP1MAPTHSD17B10CYP3A4 | |
| SCHEMBL11674589 | 0.84 | TDP1 (0.62) | NR1I2TDP1MAPTHSD17B10CYP3A4 | |
| SCHEMBL16181512 | 0.84 | PTGS1 (0.49) | NR1I2TDP1MAPTHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065621-A | Process for 3-alkyl and 3-phenyl cephalosporins | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4013651-A | 3-SUBSTITUTED AMINO-CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |