SCHEMBL11673166

SCHEMBL11673166

O=C(O)C(=C/c1ccc(N(c2ccccc2)c2ccccc2)cc1)/C(=C\c1ccc(N(c2ccccc2)c2ccccc2)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.58
KMT2A Q03164 4/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 2/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
HTT P42858 1/20 0.47
MEN1 O00255 3/20 0.44
AKR1C3 P42330 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TRPM8 Q7Z2W7 2/20 0.42
AKR1C1 Q04828 1/20 0.41
PSMD14 O00487 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11673168 1.00 TP53 (0.58) TP53KMT2AALDH1A1MAPTLMNA
SCHEMBL11673262 0.81 AKR1C3 (0.69) TP53KMT2AALDH1A1MAPTLMNA
SCHEMBL15338484 0.81 LMNA (0.46) TP53KMT2AALDH1A1MAPTLMNA
SCHEMBL8720963 0.81 KMT2A (0.54) KMT2AALDH1A1MAPTLMNAGAA
SCHEMBL4972259 0.81 TP53 (0.68) TP53KMT2AALDH1A1MAPTLMNA
SCHEMBL4972255 0.81 TP53 (0.68) TP53KMT2AALDH1A1MAPTLMNA
SCHEMBL11673895 0.79 TBXAS1 (0.51) KMT2AALDH1A1MAPTLMNAGAA
SCHEMBL12294102 0.79 APP (0.42) TP53KMT2AALDH1A1MAPTLMNA
SCHEMBL380360 0.79 TP53 (0.40) TP53KMT2AALDH1A1MAPTLMNA
SCHEMBL13070289 0.79 LMNA (0.48) TP53KMT2AALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4018606-A Organic azo pigment sensitizers for photoconductive layers EASTMAN KODAK COMPANY (US) 1977-04-19 US disclosed
US-4018607-A Crystalline organic pigment sensitizers for photoconductive layers EASTMAN KODAK COMPANY (US) 1977-04-19 US disclosed