Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673907 | 0.86 | L3MBTL1 (0.62) | L3MBTL1BCHECNR2KDM4EHPGD | |
| SCHEMBL11672853 | 0.84 | L3MBTL1 (0.56) | L3MBTL1BCHECNR2KDM4EHPGD | |
| SCHEMBL11673920 | 0.81 | L3MBTL1 (0.92) | L3MBTL1BCHECNR2CYP2C19ATM | |
| SCHEMBL11673894 | 0.81 | L3MBTL1 (0.69) | L3MBTL1BCHECNR2KDM4EHPGD | |
| SCHEMBL11672097 | 0.78 | CYP2C19 (0.67) | L3MBTL1CNR2KDM4EHPGDMEN1 | |
| SCHEMBL11672355 | 0.78 | L3MBTL1 (0.64) | L3MBTL1BCHECNR2KDM4EHPGD | |
| SCHEMBL11671924 | 0.78 | APP (0.64) | L3MBTL1BCHECNR2CNR1 | |
| SCHEMBL7068281 | 0.77 | L3MBTL1 (0.67) | L3MBTL1BCHECNR2KDM4EMEN1 | |
| SCHEMBL11844885 | 0.77 | EYA3 (0.68) | EYA3 | |
| SCHEMBL11673639 | 0.77 | CYP2C19 (0.67) | L3MBTL1BCHEKDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024273-A | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |