Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672355 | 0.91 | L3MBTL1 (0.64) | L3MBTL1KMT2AMEN1LMNAGAA | |
| SCHEMBL11734608 | 0.91 | L3MBTL1 (0.64) | L3MBTL1KMT2AMEN1LMNAMAPT | |
| SCHEMBL27784285 | 0.89 | KMT2A (0.63) | L3MBTL1KMT2AMEN1LMNAMAPT | |
| SCHEMBL11673639 | 0.87 | CYP2C19 (0.67) | L3MBTL1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5579331 | 0.86 | KDM4E (0.57) | L3MBTL1KMT2AMEN1LMNAMAPT | |
| SCHEMBL11735500 | 0.85 | L3MBTL1 (0.92) | L3MBTL1CNR2NPC1BCHECNR1 | |
| SCHEMBL11673920 | 0.85 | L3MBTL1 (0.92) | L3MBTL1CNR2NPC1BCHECNR1 | |
| SCHEMBL11732285 | 0.83 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1LMNAMAPT | |
| SCHEMBL31314572 | 0.83 | RAB9A (0.70) | L3MBTL1KMT2AMEN1LMNAMAPT | |
| SCHEMBL11181979 | 0.82 | CYP2C19 (0.67) | L3MBTL1KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731098-B1 | Alpha-substituted-3-benzyl-benzofurans | LILLY CO ELI (US) | 2003-06-18 | — | — | EP | disclosed |