Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673108 | 0.87 | CYP2C19 (0.64) | L3MBTL1EYA3CYP2C19CYP2C9MEN1 | |
| SCHEMBL11673907 | 0.84 | L3MBTL1 (0.62) | L3MBTL1CYP2C19KDM4EALDH1A1HPGD | |
| SCHEMBL11673357 | 0.84 | L3MBTL1 (0.62) | L3MBTL1EYA3CYP2C19CYP2C9MEN1 | |
| SCHEMBL11672097 | 0.81 | CYP2C19 (0.67) | L3MBTL1CYP2C19CYP2C9MEN1KMT2A | |
| SCHEMBL11672355 | 0.81 | L3MBTL1 (0.64) | L3MBTL1EYA3CYP2C19CYP2C9MEN1 | |
| SCHEMBL7068281 | 0.80 | L3MBTL1 (0.67) | L3MBTL1EYA3CYP2C19MEN1KMT2A | |
| SCHEMBL11673639 | 0.80 | CYP2C19 (0.67) | L3MBTL1EYA3CYP2C19CYP2C9MEN1 | |
| SCHEMBL11727292 | 0.80 | L3MBTL1 (0.56) | L3MBTL1EYA3CYP2C19CYP2C9MEN1 | |
| SCHEMBL9444916 | 0.80 | CYP2C19 (0.77) | EYA3CYP2C19CYP2C9MEN1KMT2A | |
| SCHEMBL11724757 | 0.76 | EYA3 (0.66) | L3MBTL1EYA3CYP2C19CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024273-A | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |