Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769555 | 0.77 | NPSR1 (0.52) | NPSR1GAAHTTTP53KMT2A | |
| SCHEMBL23009384 | 0.77 | KMT2A (0.51) | GAAHTTKMT2AMEN1POLB | |
| SCHEMBL5868364 | 0.77 | ALDH1A1 (0.54) | NPSR1GAAHTTKMT2AMEN1 | |
| SCHEMBL11674241 | 0.76 | POLB (0.46) | NPSR1HTTTP53TSHRKMT2A | |
| SCHEMBL11674696 | 0.76 | KMT2A (0.47) | NPSR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10949416 | 0.75 | NPSR1 (0.50) | NPSR1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL407836 | 0.75 | L3MBTL1 (0.50) | NPSR1GAAHTTLMNATSHR | |
| Hydrochloric Acid SCHEMBL11848832 | 0.74 | KMT2A (0.46) | NPSR1KMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8355067 | 0.74 | ADRA2C (0.49) | NPSR1GAAHTTLMNATSHR | |
| SCHEMBL9769553 | 0.72 | ALDH1A1 (0.58) | NPSR1ALDH1A1POLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017540-A | INSECTICIDES, MITICIDES | THE UPJOHN COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3932661-A | Anthelmintic methods employing benzoyl chloride phenylhydrazones | THE UPJOHN COMPANY (US) | 1976-01-13 | — | — | US | disclosed |