Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677032 | 0.87 | ADRA2A (0.42) | TSHRNR1H2NR1H3CNR2MEN1 | |
| SCHEMBL11676946 | 0.85 | TSHR (0.37) | TSHRNR1H2NR1H3CNR2MEN1 | |
| SCHEMBL11677239 | 0.81 | TSHR (0.44) | TSHRNR1H2NR1H3CNR2MEN1 | |
| SCHEMBL11676210 | 0.81 | PPARG (0.41) | TSHRCNR2MEN1KMT2AMAPT | |
| SCHEMBL11676805 | 0.81 | ADRA2A (0.44) | TSHRNR1H2NR1H3CNR2MEN1 | |
| SCHEMBL11677173 | 0.79 | TSHR (0.37) | TSHRNR1H2NR1H3CNR2MEN1 | |
| SCHEMBL11676747 | 0.78 | SLC6A4 (0.42) | KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL11675539 | 0.77 | TSHR (0.43) | TSHRMEN1KMT2AMAPTHTT | |
| SCHEMBL11676994 | 0.77 | NOS2 (0.45) | TSHRMEN1KMT2AMAPTHTT | |
| SCHEMBL11674550 | 0.77 | NISCH (0.43) | TSHRNR1H2NR1H3CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051084-A | BENZOTHIAZOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4051117-A | Triazole-azo-phenyl cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |