Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677032 | 0.89 | ADRA2A (0.42) | TSHRTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11674530 | 0.85 | TSHR (0.40) | TSHRTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11675539 | 0.84 | TSHR (0.43) | TSHRPPARAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11676994 | 0.82 | NOS2 (0.45) | TSHRMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL11677173 | 0.81 | TSHR (0.37) | TSHRTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11676805 | 0.81 | ADRA2A (0.44) | TSHRTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11676210 | 0.81 | PPARG (0.41) | TSHRPPARAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11676747 | 0.80 | SLC6A4 (0.42) | KMT2AMAPTSLC6A4 | |
| SCHEMBL11677239 | 0.78 | TSHR (0.44) | TSHRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11677289 | 0.74 | PPARA (0.37) | TSHRPPARATP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051084-A | BENZOTHIAZOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4051117-A | Triazole-azo-phenyl cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |